Anatomy & Physiology Handout

Handout on Anatomy & Physiology I

Contents

Introduction to Anatomy and Physiology

What is Anatomy? Anatomy is the branch of science that studies the structure of the human body. It focuses on understanding the physical parts of the body—like bones, muscles, and organs—and how they are organized and interconnected.

What is Physiology? Physiology, on the other hand, deals with the functions of these body parts. It explains how different organs and systems work together to keep the body alive and healthy. While anatomy tells you what a body part looks like and where it is, physiology tells you how it works.

Example to Help Understand: Think of the body as a car. Anatomy would explain what each part of the car looks like (the engine, tires, steering wheel) and where they are located. Physiology would explain how the car parts work together to make the car move (the engine creates power, the tires turn, and the brakes stop the car). Similarly, in the human body, anatomy describes the structure, while physiology describes how the structures function together.

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1. General Structure of the Body

1.1 Introduction to Anatomy and Physiology 

In this course, you’ll learn both anatomy (the “what” and “where” of body parts) and physiology (the “how” and “why” of their functions). As future nurses, this knowledge is essential for understanding how the body functions in health and illness.

1.2 Organization of the Human Body

The human body is organized in a way that allows all parts to work together. It is made up of:

  • Cells: The smallest building blocks of life.
  • Tissues: Groups of cells that perform a similar function.
  • Organs: Tissues that work together to perform a specific job (e.g., the heart pumps blood).
  • Systems: Groups of organs that perform complex functions (e.g., the digestive system breaks down food).

Understanding this organization helps you see how each small part contributes to the whole. For example, if one organ fails, it can affect the entire system (just like a broken part in a car affects how the whole car runs).

1.3 Anatomical Positions and Directions

When studying the body, we use standard terms to describe positions and directions, which makes it easier to talk about where something is located.

  • Anatomical Position: This is the reference point where the person is standing upright, arms at their sides, and palms facing forward.
  • Directional Terms:
    • Superior: Above (e.g., the head is superior to the chest).
    • Inferior: Below (e.g., the feet are inferior to the knees).
    • Anterior (or ventral): Toward the front (e.g., the belly button is anterior to the spine).
    • Posterior (or dorsal): Toward the back (e.g., the spine is posterior to the chest).

Introducing Each Body System

2. The Cell: The Building Block of Life

What is a Cell? A cell is the basic unit of life. Every part of the human body is made of cells. Each cell has specific parts that work together to keep the body functioning properly.

  • Nucleus: The control center, where instructions for the cell’s activities are stored.
  • Cytoplasm: A jelly-like fluid that holds all the cell parts.
  • Cell Membrane: The protective outer layer that controls what goes in and out of the cell.

Why Do We Need Cells? Without cells, the body cannot function. Cells work together to form tissues and organs that perform essential tasks, such as breathing, digestion, and movement.

3. The Skeletal System: Structure and Function

What is the Skeletal System? The skeletal system is made up of all the bones in your body. It provides structure, support, and protection, allowing the body to stand, move, and function properly.

Key Functions of the Skeletal System:

  • Support: Bones give the body shape and support the weight of muscles and organs.
  • Movement: Bones work with muscles to help you move. For example, when you lift your arm, your bones and muscles work together.
  • Protection: Some bones protect vital organs. For example, the ribcage protects the heart and lungs.
  • Blood Cell Production: Bones produce blood cells inside a special tissue called bone marrow.
  • Mineral Storage: Bones store minerals like calcium, which are essential for many body functions.

3.1 Axial and Appendicular Skeleton

The skeleton is divided into two main parts:

  • Axial Skeleton: Includes the skull, vertebral column (spine), and ribcage. It supports and protects the body’s central axis.
  • Appendicular Skeleton: Includes the bones of the arms, legs, pelvis, and shoulders, allowing movement.

Example for Beginners: Think of the axial skeleton as the “core” of your body that provides a strong foundation. The appendicular skeleton is like the “limbs” that help you move.

3.2 Types of Bones

  • Long Bones: Found in the arms and legs (e.g., the femur in your thigh).
  • Short Bones: Found in the wrists and ankles, allowing for fine movements.
  • Flat Bones: Protect organs, like the ribs and the skull.
  • Irregular Bones: Have complex shapes, like the bones in the spine.

Scenario: Imagine a patient with a broken arm. A long bone, like the humerus, is affected, and understanding the structure of this bone helps nurses assist in proper treatment and rehabilitation.

See Also: What foods damage your kidneys?

3.3 Joints

Joints are where two or more bones meet. They allow for movement in different directions:

  • Fixed Joints: Don’t allow movement, like those in the skull.
  • Movable Joints: Allow a range of movements, like the knee or shoulder.

Example: If someone sprains their ankle, they’ve injured the joint that allows the foot to move up and down.


4. Muscular System: Types and Functions

What is the Muscular System? The muscular system is made up of all the muscles in your body. Muscles are responsible for movement, posture, and even generating heat.

Key Functions of the Muscular System:

  • Movement: Muscles contract (shorten) to pull on bones, which results in movement. For example, you use your leg muscles to walk.
  • Posture: Even when you’re standing still, muscles help maintain your posture by keeping your body upright.
  • Heat Production: Muscles generate heat when they contract, helping to maintain body temperature.

4.1 Types of Muscles

There are three types of muscles in the body:

  • Skeletal Muscle: These are voluntary muscles, meaning you control them. They are attached to bones and help you move (e.g., biceps, quadriceps).
  • Smooth Muscle: These are involuntary muscles, meaning they work automatically without you thinking about it. They are found in organs like the intestines and blood vessels, helping with digestion and blood flow.
  • Cardiac Muscle: This is also an involuntary muscle but is found only in the heart. It helps pump blood throughout the body.

Scenario: When you pick up a cup, you use skeletal muscles in your arm. When your heart beats, cardiac muscles are at work, and when your stomach digests food, smooth muscles help push the food through.

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4.2 How Muscles Work (Muscle Contraction and Relaxation)

Muscles work by contracting (shortening) and relaxing (lengthening). For example, when you bend your arm, your bicep contracts, and when you straighten your arm, your tricep relaxes.

Clinical Application Example: Nurses often monitor muscle contractions in patients after surgery or injury to ensure muscles are functioning properly and there is no nerve damage.


5. Cardiovascular System: The Heart and Blood Vessels

What is the Cardiovascular System? The cardiovascular system is responsible for transporting blood, oxygen, and nutrients throughout the body. It includes the heart, blood vessels, and blood.

5.1 The Heart: Structure and Function

The heart is a muscular organ located in the chest. Its job is to pump blood through the body. It has four chambers:

  • Atria: The upper chambers that receive blood.
  • Ventricles: The lower chambers that pump blood out of the heart.

Key Functions of the Heart:

  • Pumps oxygen-rich blood to the body.
  • Pumps oxygen-poor blood to the lungs to get oxygenated.

5.2 Blood Vessels: Arteries, Veins, and Capillaries

  • Arteries: Carry oxygen-rich blood away from the heart to the rest of the body.
  • Veins: Carry oxygen-poor blood back to the heart.
  • Capillaries: Tiny blood vessels where oxygen and nutrients are exchanged with tissues.

Example: Think of arteries as highways that carry blood from the heart to your muscles, veins as roads that bring it back, and capillaries as small streets where exchanges take place.

5.3 Blood Composition

Blood is made up of different components:

  • Red blood cells (RBCs): Carry oxygen to all parts of the body.
  • White blood cells (WBCs): Fight infections.
  • Platelets: Help with clotting when you get a cut.
  • Plasma: The liquid part of blood, which carries nutrients, hormones, and waste products.

Scenario: Nurses often perform blood tests to check for conditions like anemia (low RBC count) or infections (high WBC count). Blood transfusions may be given if there is a deficiency in one of these components.

5.4 Circulation of Blood

There are two types of circulation:

  • Pulmonary Circulation: Blood flows from the heart to the lungs and back to the heart to get oxygen.
  • Systemic Circulation: Blood flows from the heart to the rest of the body to deliver oxygen.

Scenario: Understanding blood flow is essential when caring for patients with heart disease. For example, if the heart can’t pump blood properly, it can lead to conditions like heart failure.


6. Urinary System: Structure and Function

What is the Urinary System? The urinary system removes waste from the body and helps control fluid and electrolyte balance. It includes the kidneys, ureters, bladder, and urethra.

6.1 Key Functions of the Urinary System

  • Filtration of Blood: The kidneys filter waste from the blood to form urine.
  • Excretion of Waste: Urine carries waste products out of the body.
  • Regulation of Fluid and Electrolyte Balance: The kidneys ensure that the body has the right balance of fluids and electrolytes, like sodium and potassium.

6.2 Organs of the Urinary System

  • Kidneys: These bean-shaped organs filter waste from the blood.
  • Ureters: Tubes that carry urine from the kidneys to the bladder.
  • Bladder: Stores urine until it is ready to be expelled.
  • Urethra: The tube that carries urine from the bladder out of the body.

Scenario: In patients with kidney failure, waste can build up in the blood, leading to serious health problems. Nurses must monitor urine output and blood tests to assess kidney function.

Read Also: How to Calculate GPA and CGPA on HTI Portal

7. Lymphatic System: Structure and Function

What is the Lymphatic System? The lymphatic system helps the body get rid of waste and toxins, and it plays a critical role in the immune system. It includes a network of lymph vessels, lymph nodes, and lymph (a fluid that contains white blood cells).

7.1 Key Functions of the Lymphatic System

  • Fluid Balance: It collects excess fluid from tissues and returns it to the bloodstream.
  • Immune Defense: Lymph nodes filter out harmful substances like bacteria and viruses. White blood cells in the lymph fight infections.
  • Absorption of Fat: The lymphatic system absorbs fats from the digestive system and transports them to the bloodstream.

7.2 Parts of the Lymphatic System

  • Lymph: The clear fluid that circulates through the lymphatic system, carrying immune cells.
  • Lymph Vessels: Network of tubes that transport lymph throughout the body.
  • Lymph Nodes: Small, bean-shaped structures that filter harmful substances from lymph and contain immune cells that fight infection.
  • Lymphoid Organs: These include the spleen, thymus, and tonsils, which are important for immune function.

Scenario: Swollen lymph nodes are often a sign of infection, such as a sore throat. Nurses assess lymph nodes to determine the cause of the swelling and recommend treatment.

7.3 Lymphatic Circulation

Lymph flows through lymph vessels and passes through lymph nodes where it is filtered. The lymph is then returned to the bloodstream. The flow of lymph depends on muscle movement and valves that prevent backflow.

Clinical Application: In conditions like lymphedema (swelling due to a blockage in the lymphatic system), nurses play a key role in managing the condition by recommending compression therapy and physical exercises to encourage lymph flow.


8. Integumentary System: Structure and Function

What is the Integumentary System? The integumentary system consists of the skin, hair, nails, and glands. It serves as the body’s outer covering and protects against injury, infection, and dehydration.

8.1 Key Functions of the Skin

  • Protection: The skin acts as a barrier to protect the body from infections, harmful UV rays, and physical damage.
  • Temperature Regulation: Sweat glands in the skin help regulate body temperature. When the body overheats, sweat evaporates to cool it down.
  • Sensation: The skin contains nerve endings that detect touch, pain, heat, and cold.
  • Excretion: Sweat glands also help remove waste products, like salts and water, from the body.
  • Vitamin D Production: The skin produces vitamin D when exposed to sunlight, which is essential for healthy bones.

8.2 Layers of the Skin

  • Epidermis: The outermost layer, which provides a waterproof barrier and creates skin tone.
  • Dermis: Below the epidermis, it contains tough connective tissue, hair follicles, and sweat glands.
  • Hypodermis (Subcutaneous Layer): The deeper layer, made of fat and connective tissue, helps insulate the body and cushion internal organs.

Example for Beginners: Imagine the skin as a protective coat. The outer layer (epidermis) is like a raincoat, keeping water out. The middle layer (dermis) is like the coat’s lining, providing warmth and support. The inner layer (hypodermis) is like the insulation, protecting what’s underneath from damage.


9. The Urinary System 

9.1 Physiology of Urine Formation

The kidneys filter waste and excess substances from the blood to produce urine through three main steps:

  1. Filtration: Blood enters the kidneys, where waste, water, and small molecules are filtered out.
  2. Reabsorption: Useful substances like glucose, water, and ions are reabsorbed back into the blood.
  3. Secretion: The kidneys add any extra waste products to the filtrate, which becomes urine.

Scenario: Patients with diabetes may have glucose in their urine because their bodies can’t reabsorb all of the sugar from their blood. Nurses monitor urine tests to detect this and manage the condition.

9.2 Composition of Urine

Urine is mainly water, but it also contains waste products like urea, creatinine, and various electrolytes. The color, odor, and composition of urine can indicate health problems.

Example: Dark yellow urine may indicate dehydration, while cloudy urine could be a sign of a urinary tract infection (UTI).

9.3 Fluid-Electrolyte and Acid-Base Balance

The kidneys help maintain a balance of fluids and electrolytes (such as sodium and potassium) in the body. They also regulate the pH level by excreting hydrogen ions and reabsorbing bicarbonate, which keeps the blood’s acidity in check.

Clinical Application: Nurses must monitor patients for signs of fluid or electrolyte imbalance, especially in those receiving intravenous fluids, to prevent conditions like hyperkalemia (high potassium levels) or dehydration.


10. Cardiovascular System 

10.1 Blood Pressure and Heart Function

Blood Pressure (BP): The force of blood against the walls of blood vessels. It’s an important measure of heart health. Normal BP is typically around 120/80 mmHg.

  • Systolic BP: The pressure when the heart pumps blood (the top number).
  • Diastolic BP: The pressure when the heart is resting between beats (the bottom number).

Scenario: High blood pressure (hypertension) increases the risk of heart disease and stroke. Nurses routinely monitor BP in patients and provide education on managing high BP through diet, exercise, and medication.

10.2 Blood Composition 

Blood is composed of:

  • Red Blood Cells (RBCs): Carry oxygen from the lungs to the rest of the body.
  • White Blood Cells (WBCs): Help fight infections and are part of the immune system.
  • Platelets: Assist in blood clotting to prevent excessive bleeding.
  • Plasma: The liquid portion of blood that transports nutrients, hormones, and waste products.

Scenario: After surgery, patients may have low RBC levels due to blood loss. Nurses monitor blood tests and may administer blood transfusions if necessary.

10.3 Cardiac Output and Circulation

Cardiac Output (CO): The amount of blood the heart pumps in one minute. It’s a critical measure of how well the heart is functioning.

  • Systemic Circulation: Delivers oxygenated blood from the heart to the rest of the body.
  • Pulmonary Circulation: Carries deoxygenated blood to the lungs for oxygenation.

Clinical Application: In heart failure patients, cardiac output may decrease, leading to fatigue and fluid retention. Nurses play a crucial role in managing symptoms and adjusting treatments like medications or fluid restriction.


This handout provides a beginner-friendly introduction to the core concepts of anatomy and physiology. By breaking down complex terms into simpler explanations, students can build a strong foundation for understanding the human body. In clinical practice, this knowledge will help nurses provide effective care, from recognizing abnormal vital signs to understanding the mechanisms behind common health conditions.

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